Cabozantinib Malate API

Cabozantinib Malate API is an active pharmaceutical ingredient used in oncology therapeutic applications.

Applications of Cabozantinib Malate

• Cabozantinib malate is a small-molecule multi-target tyrosine kinase inhibitor used in oncology research and pharmaceutical development. It primarily targets VEGFR2, MET, FLT3, TIE2, KIT, and RET signaling pathways, playing a key role in inhibiting tumor angiogenesis and cancer cell proliferation. Cabozantinib malate demonstrates dose-dependent inhibition of tumor growth and tumor regression. This mechanism is associated with disruption of tumor vasculature and induction of cancer cell apoptosis. This API is widely used in pharmaceutical R&D and oral solid dosage formulation development, and supports preclinical and clinical stage drug development programs.
• Cabozantinib Malate API is extensively used in oncology formulation development, particularly in oral solid dosage forms such as tablets and capsules, supporting formulation optimization and preclinical research studies.
• Cabozantinib Malate plays an important role in pharmaceutical process development and scale-up production, including impurity control, crystallization studies, and quality consistency evaluation during commercial manufacturing.
• Cabozantinib Malate API is suitable for use in both early-stage research and late-stage pharmaceutical development programs. It provides consistent quality performance required for formulation screening, bioavailability evaluation, and stability assessment in oral solid dosage development. The API is also compatible with various process development workflows, supporting optimization of manufacturing parameters and scale-up activities in regulated pharmaceutical environments. With stable physicochemical properties, it enables reproducible results in laboratory and pilot-scale studies, making it a reliable active ingredient for oncology-focused drug development pipelines.
• Cabozantinib Malate API is supported by consistent analytical quality control systems, including HPLC-based impurity profiling and stability-indicating methods, ensuring reliable performance across different stages of pharmaceutical development and regulatory submission requirements.

Why Choose Us as Your Manufacturer?

• Qingmu’s factory is established according to ICH/USFDA/EU/JAPAN/China regulations and current GMP, totally complies with environmental law in China, no risk to remove factory.
• Qingmu’s team has rich experience in patent challenges on crystalline form & synthesis processes and also synthetic route development and scale-up & quality research. We are always responsible for our products.
• Qingmu’s lab is equipped with HPLC, GC, ICP-MS, GC-MS, CAD, microbalance, Malvern particle analyzer, etc. We passed the site inspection from NMPA(China), FDA(USA) and MFDS(Korea) and also customer audits from Europe, USA and Japan, etc.
• As a manufacturer, Qingmu successfully exported products to more than 40 countries including Japan, USA, Germany, Spain, the Netherlands, Russia, South Korea, and Brazil.

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